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Friday, November 15, 2019

Histology of Mammal By. Dr. Vidhin Kamble Sangola College, Sangola



V. S. of  TOOTH of Mammal
 
1. Teeth are present in bucal cavity.
2.  Tooth is distinguished in to crown, neck and root.
3.  Crown is the exposed part of the tooth which projects out of the jaws in the oral
cavity and is white glistening in appearance.
4.  Neck is the middle part of the tooth which is above the root surrounded by the gum.
5. Root is present in the bony socket of jaw bone or alveolus.
6. The vertical section o tooth shows following histological parts.
A) Pulp cavity B) Dentine C) Cement D) Enamel
Cavity enclosed by tooth is called pulp cavity. Pulp cavity is surrounded by relatively soft dentine.  Tooth is fitted into the socket of jaw by cement substance. Enamel is hardest part of tooth, covering dentine from all side.
Function of tooth: Mastication of Food


 SALIVARY GLAND

1.  Salivary glands are also called as parotid glands.
2.  It is a tubular or  alveolar gland.
3.  secretes saliva contains digestive enzyme ptyalin.
4.  Each salivary gland consists of large number of lobules bound together by connective tissue, blood vessels, nerves and numerous fat cells.
5.  Each lobule consists of alveoli or acini, lined by mucus cells and serous cells.
6.  From alveoli arises  duct  unites to form a salivary duct which opens into the mouth.
7.  Histologically salivary gland shows three types of cells which are as follows.
a) Serous cells secrete ptyalin.
b) Mucous cells secrete mucous and
c) Crescent cells - replace worn out cells.
Function of Salivary gland:
1. Saliva helps in moistening of food particle.
2. Salivary amylase act upon carbohydrates.  


T. S. of Stomach of Mammal


Stomach is bag like structure.
1.   Histologically the stomach shows following parts
2.  Serosa
3.  muscularis externa
4.  Sub-mucosa
5.  Muscularis mucosa
6.  Mucosa
a.  Outer most layer of stomach is called serosa is made up of squamous epithelium.
b.  Muscularis externa consists of outer longitudinal and inner circular muscle layer.
c.    Below the muscularis there is a sub mucosa made up of connective tissue containing blood vessels, nerves and lymph vessels.
d.   Below the sub mucosa there is  muscularis mucosae consists of two layers of muscle . according to their plan they are called  longitudinal muscle layer  and circular muscle layer
e.   The muscularis mucosae is followed by a thickest layer called mucosa consists  of simple columnar epithelium and gastric glands.
f.    The gastric glands are long and arranged parallel to each other. These are  simple or simple tubular gland.
g.  The gastric glands consists  of two types of cells namely oxyntic and peptic cells.
h.  The peptic cells secrete digestive enzymes and oxyntic cells secrete HCl.
Function of stomach:
1.  Digestion of food.
2.  Secretion of gastric juice.
3.  Gastric juice contains HCl and Pepsin.



Histology of Intestine

The intestine is long tube like divisible into Small intestine and large intestine. The small intestine consists of Duodenum and Ilium, while large intestine consist of Colon and Rectum. 






T. S. of  Ilium of Mammal



Histologically, the ileum has the same basic structure as the jejunum:



1.     Serosa

2.  muscularis externa

3.  Sub-mucosa

4.  Muscularis mucosa

5.  Mucosa


1.     Outer most layer of stomach is called serosa is made up of squamous epithelium.
2.     Muscularis externa consists of outer longitudinal and inner circular muscle layer.
3.     The submucosa contains is made up of connective tissue containing blood vessels, nerves,  lymph nodes and the Meissner’s plexus.
4.      Below the sub mucosa there is  muscularis mucosae consists of two layers of muscle . Accordingly, they are called  longitudinal muscle layer  and circular muscle layer.
5.     The muscularis mucosae is followed by a thickest layer called mucosa
6.     The mucosa membrane of ilium shows large and small finger like folds called villi covered by simple columnar epithelium with dispersed goblet cells.
7.     Each villus shows presence of blood vessels, lymph vessels and lacteal.
8.     At the base between the villi Crypts of Liberkuhn are present which  lead into Bruner's gland.
4. The secretion of these glands forms digestive juices.
 The secretions of these glands form digestive juices.



T. S. of Liver of Mammal

Liver is the largest digestive gland. Histologically it shows following parts.
1. The liver is composed of polygonal lobules containing a central vein in the centre and the portal canal at the corners.
2 Each portal canal consists of connective tissue strand and contains a
branch of portal vein, hepatic artery, bile duct and lymph vessel.
3. The liver cells are polyhedral or rectangular and arranged in single celled
long chains extending radially from the central vein to the periphery of the
lobule.
4. Each liver cell has granular cytoplasm and a prominent nucleus.
Function of liver
Liver has several functions.
Liver produces bile which plays important role in the digestion of food.
7. It stores the soluble products of digestion and metabolizes them for
assimilation.
9.     In liver toxic substances are detoxicated in the liver.
10.          It helps in emulsification of fat.


T. S. of Pancreas 

Pancreas is exocrine as well as endocrine in function.
1. The pancreas consists of two portions namely endocrine and exocrine portion.
2. The exocrine portion consists of a series of lobules or acini; bound together by connective tissue containing blood vessels, nerve endings and lymph vessels.
3. Each lobule or acinus is made up of pyramidal pancreatic cells having
granular cytoplasm and prominent nuclei.
4. The lobules or acini open into small ductules which join to form large ducts and which finally form the main pancreatic duct.
6. The endocrine portion consists of Islets of Langerhans between the acini.

Functions of pancreas
1.The exocrine portion of pancreas produces pancreatic juice which contains trypsin, amylase and lipase enzymes.
     2. Endocrine part  produces two hormones.
         a. Insulin produced by beta cells.
         b. Glucagon produced by alpha cells.





T. S. of Kidney  of Mammal
 
Kidney is main part of excretory system which help in removal of nitrogenous waste.
1. Each kidney is bean shaped.
The kidney is surrounded by a capsule of dense connective tissue.
2. Kidney is composed of outer cortex and inner medulla.
3 The cortex contains numerous uriniferous tubules having Bowman's capsules and glomeruli
4 The medulla is consists of some renal pyramids consisting of modularly rays, columns of Bertini, tubules of medulla and connective tissue.
Function of Kidney
a.     Removal of nitrogenous wastes from body.
b.     Maintenance of water balance inside of body (Osmoregulation)



T. S. Of  Testis of Mammal

Testis are the male gonads.
1. The testis is somewhat oval or rounded in shape surrounded peritoneum
followed by a layer of fibrous connective tissue, the tunica albuginea.
2.     Histologically each testis shows presences of convoluted seminiferous tubules separated from one another by inter tubular connective tissue.
3.     In connective tissue blood vessels and interstitial cells (Leydig cells)  are present.
4.     The interstitial cells secrete a hormone testosterone  
5.     Each seminiferous tubule is oval or rounded in appearance and   surrounded by basement membrane and lined by germinal epithelium
6.     Seminiferous tubule shows presence varous stages of developing sperms includes,  spermatogonia, primary spermatocytes, secondsry spermatocytes and spermatids.
7.     In between the germinal cells certain large sertoli cells are present
Function of Testis
a.     Seminiferous tubule produces sperm.
b.    Interstitial cells secret male sex hormone called testostron which control male secondary sex character
c.     Sertoli cells of seminiferous tubule supplying nourishment to the developing sperms.


T. S. of Ovary of Mammal

Ovary is female  gonad.
1. The ovary is lined by germinal epithelium which is bounded by the connective tissue, the tunica albuginea.
2. The mass of the ovary is called stroma formed of connective tissue rich in
elastic fibers with large blood vessels lymphatic's and nerves.
3. In the stroma are egg cells in the various stages of development, each
surrounded by a nourishing epithelial layer, the follicle and blood vessels.
4. Ovary in  the stroma shows, presence of various stages of developing ova. It includes,  primary follicle (ovum and single layer of
follicle cells), secondary follicle (double layered follicle), mature follicle with antrum, ruptured follicle, fully formed corpus luteum and corpus albicans.
5. The primary follicles develop from primordial follicles present in the germinal epithelium.
6 The follicle and ovum slowly move deeper in to the stroma and become
larger.
Mature follicles shows presence of follicular cavity filled with follicular fluid called oestrogne.
7. Later ovum and cells around it become separated by fluid filled space from the rest of the follicle except at one point forming antrum.
8. The enlargement of the ovum and follicle results in the formation of a mature follicle or graffian follicle.
Function of ovary
a.     Production of ova.
b.     Developing follicle produces oestrogen hormone which control female secondary sex characters. 




T. S. of Uterus


Uterus is hollow pear shaped thick walled structure present between vagina and fallopian tube.
It consists of fundus, corpus and cervix.
2. Histologically the wall of the uterus shows three layers
1) Primetrium or Serosa
 2) Myometrium or muscularis
3) Endometrium or mucosa.

1. Primetrium or serosa: it is the outer most protective coat forming the broad ligament through which blood vessels, lymphatics and nerves reach the uterus
2. Myometrium or muscularis: this is the middle muscular coat of uterus. it is very thick layer consists of smooth muscle fibers, connective tissue and large  blood vessels.
it consists of three sets of muscle layers and accordingly they are called as outer longitudinal muscle, middle oblique muscle and inner circular muscles.
Oxytocin hormone secreted by pituitary gland control the movement of these muscles.  
3. Endometrium or mucosa: it is the inner most layer of uterus occupies major portion of lumen of uterus. The endometrium consists of two membrane.
a. Inner Endometrium functionalis
b. Outer Endometrium basalis.
a. The endometrium functionalsi is lined by mucosal epithelium linded by simple columnar ciliated epithelium and underlying submucosa. Endometrium functionalis undergoes cyclic changes during menstruation.
The stroma of uterine wall consists of simple tubular uterine glands.  
b. Endometrium basalis: this is the region of uterus remain unchanged during disrutvie phase of sex cycle or menstrual cycle.
 

 

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